A weekly digest of peer-reviewed, open-access research in periodontology, dental implantology, and peri-implant medicine. Articles are selected and summarized by Dr. Ernesto Bruschi — periodontist, implantologist, and oral surgeon.
Wu Y, Zheng L, Song C
Periodontal pathogens have long been implicated in cardiovascular disease, but direct evidence linking bacterial detection — rather than periodontal diagnosis alone — to coronary heart disease (CHD) has remained limited....
Read more →Kafle S, Gupta A, Khatiwada S
Periodontitis and diabetes are known to interact bidirectionally, but data from South Asian populations — where both conditions are highly prevalent and often under-managed — remain sparse. This hospital-based cross-sect...
Read more →Inan B, Parlak HM, Akcicek G
Adequate keratinized mucosa width (KMW) around implants is widely accepted as protective, but whether vestibule depth (VD) — a related but distinct anatomical measure — independently contributes to peri-implant soft tiss...
Read more →RawenTonini K, Hadad H, Egas LS
Systemic disease is often treated as a relative contraindication—or at least a risk factor requiring extra caution—for dental implant placement, but the actual magnitude of that risk in modern practice is debated. This r...
Read more →Park SH, Kim DM, Song YW
Enamel matrix derivative (EMD) is an established adjunct for regenerative treatment of intrabony periodontal defects, typically applied during minimally invasive surgery. Whether a fully nonsurgical application of EMD ca...
Read more →Teleka S, Persson P, Vähäsarja N
Clinical question: is periodontitis mechanistically linked to coronary heart disease (CHD) through subclinical atherosclerosis, and does it associate with inflammation in epicardial adipose tissue (EAT)? Methodology: th...
Read more →Qi X, Liu R, Belsky DW
Clinical question: does tooth loss (edentulism) predict cognitive decline and dementia, and is this association mediated by blood-based markers of neurodegeneration? Methodology: 4,238 participants aged 50+ from the nat...
Read more →Lee D, Ko YC, Koo KT
Clinical question: do collagen membranes with different thickness-related mechanical properties, used to cover bone grafts in guided bone regeneration (GBR), produce different biological healing responses during lateral ...
Read more →Aghaziarati F, Chitsazi MT, Roshangar L
Clinical question: how does allogenic demineralized dentin matrix (ADDM) — a donor-derived bone graft substitute — compare with xenograft for maxillary sinus floor augmentation (MSFA) in the atrophic posterior maxilla? ...
Read more →Foad MW, El Rawdy AM, Hamed MS
Clinical question: does adding hyaluronic acid (HA) to natural bovine bone grafting material improve outcomes when grafting fresh extraction sockets around immediate implants? Methodology: randomized clinical trial, 16 ...
Read more →Botelho J, Singh S, Varenne B
Diabetes and oral disease are both massive global burdens — roughly 828 million people live with diabetes, 3.7 billion with some form of oral disease — and the two are often assumed to interact, but the direction and str...
Read more →Lu J, Wu X, Xiong Z
Lymphocytes are the principal source of RANKL in periodontitis, but exactly how they get organised and activated within inflamed gingiva has been unclear. This mechanistic study looks at tertiary lymphoid structures (TLS...
Read more →Ferrarotti F, Baima G, Campagna A
Treated periodontitis patients make up a large share of implant candidates, but whether residual probing pocket depth (PPD) left over after active periodontal therapy actually raises peri-implant risk has never been revi...
Read more →Moraschini V, de Moraes JB, de Oliveira Silva AM
Zirconia implants (ZIs) are increasingly proposed as a metal-free alternative to titanium (TIs), marketed on esthetic and biological grounds, but solid prevalence data on peri-implantitis around ZIs — and whether implant...
Read more →Littlejohn C, Chang YC, Teles F
Prophylactic antibiotics are routine before many dental surgical procedures, yet how they actually reshape the oral and gut microbiome — and whether that disruption resolves — has been surprisingly under-studied. This pr...
Read more →Fanelli F, Tisci A, Lo Muzio L
Radiographic diagnosis of peri-implantitis is notoriously operator-dependent, and measurable marginal bone loss is often detected only after the disease has progressed. This comprehensive review set out to synthesize the...
Read more →Sari A, Kaya OM, Arisan V
Oral protozoa such as Trichomonas tenax and Entamoeba gingivalis have long been observed in periodontal pockets, but their relationship to peri-implant disease has received far less attention. This cross-sectional study ...
Read more →El-Wakeel N, Abdelgawad N, Nour Eldien M
Local application of biomaterials alongside conventional periodontal surgery is an active area of research for boosting regenerative outcomes in intrabony defects. This pilot randomized controlled trial compared two cand...
Read more →Mashadiyev U, Gürkan İM, Gündoğar H
Peri-implant mucositis and peri-implantitis remain among the most common biological complications of implant therapy, but how much patient-level versus implant-level factors each contribute is still debated. This retrosp...
Read more →Topdagi B, Kurum M, Guler CC
The All-on-4 concept has become a mainstay for rehabilitating the edentulous arch, but how bone quality and prosthetic material choice interact to affect medium-term outcomes is less well documented in large, multicenter...
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