https://osteoperionews.bonebenders.com/en Curated news from the periodontal and implant literature — Dr. Ernesto Bruschi en Fri, 08 May 2026 08:57:10 GMT https://osteoperionews.bonebenders.com/en/articles/periodontitis-induces-skeletal-muscle-atrophy-by-increasing-circulating-levels-o-42091891 https://osteoperionews.bonebenders.com/en/articles/periodontitis-induces-skeletal-muscle-atrophy-by-increasing-circulating-levels-o-42091891 Wed, 06 May 2026 00:00:00 GMT Periodontitis is well established as a systemic disease driver, associated with cardiovascular risk, diabetes, and adverse pregnancy outcomes. Its relationship with skeletal muscle, however, had remained largely unexplored — until now. This study addresses a clinically underappreciated question: can active periodontal disease directly contribute to muscle wasting? Using a ligature-induced periodontitis model in male mice, the authors demonstrated that periodontal inflammation causes significant Nature communications https://osteoperionews.bonebenders.com/en/articles/clinical-parameters-subgingival-microbiota-and-mmp-8-expression-in-dental-implan-42090680 https://osteoperionews.bonebenders.com/en/articles/clinical-parameters-subgingival-microbiota-and-mmp-8-expression-in-dental-implan-42090680 Thu, 01 Jan 2026 00:00:00 GMT Dental implants and natural teeth occupy the same oral environment yet behave as distinct biological entities. This study set out to quantify those differences in clinically healthy conditions, comparing probing depth, keratinized mucosa dimensions, subgingival microbiota composition, and MMP-8 expression between 79 implants and their 79 contralateral homologous teeth in 47 patients. Implants spanned three platform designs — External Hexagon (EH), Internal Hexagon (IH), and Morse Taper (MT) — al Brazilian dental journal https://osteoperionews.bonebenders.com/en/articles/histological-and-histomorphometric-assessment-of-lateral-window-sinus-augmentati-42050510 https://osteoperionews.bonebenders.com/en/articles/histological-and-histomorphometric-assessment-of-lateral-window-sinus-augmentati-42050510 Tue, 28 Apr 2026 00:00:00 GMT Severe posterior maxillary atrophy remains one of the most demanding scenarios in implant surgery. When residual bone height drops to 4 mm or less, lateral window sinus augmentation becomes not just an option but a necessity — and the choice of grafting material directly influences the quality and quantity of the regenerated bone. This prospective histomorphometric study from a Vietnamese cohort addressed a straightforward but clinically critical question: what kind of bone does a composite gra BMC oral health https://osteoperionews.bonebenders.com/en/articles/evaluation-and-comparison-of-crestal-bone-loss-around-dental-implants-placed-usi-42064527 https://osteoperionews.bonebenders.com/en/articles/evaluation-and-comparison-of-crestal-bone-loss-around-dental-implants-placed-usi-42064527 Sun, 01 Mar 2026 00:00:00 GMT Alveolar ridge resorption following tooth loss remains one of the central challenges in implant rehabilitation. When residual ridge width is insufficient, clinicians must choose between bone expansion and ridge split techniques — yet the impact of these preparatory approaches on long-term crestal bone stability has not been rigorously compared head-to-head. This prospective comparative study addressed precisely that question. Seventy-two implant sites were enrolled across patients aged 25–55 ye Cureus https://osteoperionews.bonebenders.com/en/articles/dna-framework-based-nanomedicine-platform-a-triple-function-strategy-for-treatin-42056079 https://osteoperionews.bonebenders.com/en/articles/dna-framework-based-nanomedicine-platform-a-triple-function-strategy-for-treatin-42056079 Wed, 29 Apr 2026 00:00:00 GMT Periodontitis remains one of the most clinically challenging conditions in oral medicine: driven by polymicrobial dysbiosis, it sustains a chronic inflammatory cascade that ultimately destroys the periodontal ligament, connective tissue, and alveolar bone. Conventional treatment — scaling, root planing, adjunctive antibiotics — addresses biofilm mechanically but offers limited control over the inflammatory and regenerative axes simultaneously. This study tackles that gap with a single, multifunc International journal of oral science https://osteoperionews.bonebenders.com/en/articles/efficacy-of-different-nonsurgical-treatments-for-peri-implantitis-a-multi-arm-ra-42069893 https://osteoperionews.bonebenders.com/en/articles/efficacy-of-different-nonsurgical-treatments-for-peri-implantitis-a-multi-arm-ra-42069893 Sat, 02 May 2026 00:00:00 GMT Peri-implantitis is one of the most clinically demanding conditions in implant dentistry. Despite a growing body of literature, there is still no consensus on which nonsurgical decontamination protocol offers the best outcomes. This multi-arm randomized controlled trial by Eraydin-Tufek and colleagues set out to compare five different nonsurgical approaches in patients with early peri-implantitis, addressing a genuinely unresolved clinical question. Eighty implants from 26 patients were randoml Scientific reports https://osteoperionews.bonebenders.com/en/articles/adjunctive-use-of-locally-delivered-statins-in-periodontal-therapy-and-pre-impla-42046838 https://osteoperionews.bonebenders.com/en/articles/adjunctive-use-of-locally-delivered-statins-in-periodontal-therapy-and-pre-impla-42046838 Wed, 01 Apr 2026 00:00:00 GMT Statins have long been recognized for their pleiotropic effects beyond lipid lowering — including anti-inflammatory, angiogenic, and osteogenic properties. The clinical question driving this systematic review and meta-analysis is whether locally delivered statins, when used as adjuncts to conventional periodontal therapy or pre-implant bone regeneration procedures, produce measurable improvements in clinical and radiographic outcomes compared to standard treatment alone. The authors searched Pu Clinical and experimental dental research https://osteoperionews.bonebenders.com/en/articles/effects-of-extended-guided-bone-regeneration-on-the-labial-alveolar-wall-of-adja-42057175 https://osteoperionews.bonebenders.com/en/articles/effects-of-extended-guided-bone-regeneration-on-the-labial-alveolar-wall-of-adja-42057175 Wed, 29 Apr 2026 00:00:00 GMT Flap surgery in the anterior maxilla carries a predictable collateral cost: resorption of the thin labial alveolar wall (LAW) of teeth adjacent to the surgical site. Even when the implant site heals uneventfully, the neighboring alveolar bone can quietly deteriorate, compromising soft tissue support and the overall aesthetic outcome. This retrospective cohort study asked a straightforward clinical question: does extending the GBR graft to cover the LAW of adjacent teeth actually protect that bon Head & face medicine https://osteoperionews.bonebenders.com/en/articles/postoperative-administration-of-mesenchymal-stem-cells-enhances-peri-implant-tis-42070743 https://osteoperionews.bonebenders.com/en/articles/postoperative-administration-of-mesenchymal-stem-cells-enhances-peri-implant-tis-42070743 Fri, 01 May 2026 00:00:00 GMT Patients on antiresorptive therapy — bisphosphonates, denosumab — represent a genuine clinical dilemma when implant placement is considered. The risk of medication-related osteonecrosis of the jaw (MRONJ) is real, and no established protocol reliably neutralizes it. This study asks a precise question: can mesenchymal stem cell (MSC) therapy rescue peri-implant healing in a compromised MRONJ environment, and does the timing of administration matter? The research group developed a reproducible ra Acta biomaterialia https://osteoperionews.bonebenders.com/en/articles/efficacy-of-periodontal-therapy-in-preventing-tooth-loss-and-improving-masticato-41985956 https://osteoperionews.bonebenders.com/en/articles/efficacy-of-periodontal-therapy-in-preventing-tooth-loss-and-improving-masticato-41985956 Wed, 15 Apr 2026 00:00:00 GMT Periodontitis and chronic kidney disease (CKD) share a bidirectional inflammatory relationship that worsens systemic and oral outcomes alike. Despite growing epidemiological evidence linking the two conditions, high-quality interventional data on the impact of periodontal treatment in CKD patients remain scarce. This randomised controlled trial protocol, developed at the Ninth People's Hospital affiliated to Shanghai Jiao Tong University, addresses a clinically relevant but underexplored questio BMJ open https://osteoperionews.bonebenders.com/en/articles/guided-alveolar-ridge-preservation-g-arp-using-a-cortical-lamina-a-pilot-randomi-42041646 https://osteoperionews.bonebenders.com/en/articles/guided-alveolar-ridge-preservation-g-arp-using-a-cortical-lamina-a-pilot-randomi-42041646 Tue, 24 Mar 2026 00:00:00 GMT Alveolar ridge preservation remains one of the central challenges in implant dentistry: extraction alone triggers a well-documented cascade of dimensional changes — predominantly buccal bone resorption — that can compromise both implant placement and the final esthetic outcome. This pilot randomized controlled trial by Mainetti et al. investigates a refined approach termed Guided Alveolar Ridge Preservation (G-ARP), which combines socket grafting with the use of a cortical lamina as a structural Dentistry journal https://osteoperionews.bonebenders.com/en/articles/probiotics-and-ozonated-olive-oil-to-maintain-oral-eubiosis-in-stage-i-and-ii-pe-42041656 https://osteoperionews.bonebenders.com/en/articles/probiotics-and-ozonated-olive-oil-to-maintain-oral-eubiosis-in-stage-i-and-ii-pe-42041656 Wed, 01 Apr 2026 00:00:00 GMT Periodontitis is fundamentally a dysbiotic disease: the shift from a balanced subgingival microbiome toward a pathogen-dominated community drives the destructive host response that defines the condition. Controlling this dysbiosis — not merely reducing pocket depth — is increasingly recognized as the true target of supportive periodontal therapy. This randomized triple-blind clinical trial investigated whether the adjunctive use of probiotics and ozonated olive oil, administered during the maint Dentistry journal https://osteoperionews.bonebenders.com/en/articles/the-effectiveness-of-vitamin-d-supplementation-in-association-with-non-surgical-42041664 https://osteoperionews.bonebenders.com/en/articles/the-effectiveness-of-vitamin-d-supplementation-in-association-with-non-surgical-42041664 Mon, 06 Apr 2026 00:00:00 GMT Vitamin D has long been recognized for its immunomodulatory and anti-inflammatory properties, making it a plausible adjunct in the management of periodontal disease. This systematic review by Pesce and colleagues addresses a focused clinical question: does vitamin D supplementation, when combined with non-surgical periodontal therapy (NSPT), produce measurably better clinical outcomes than NSPT alone? The authors conducted a systematic literature search across major electronic databases, select Dentistry journal https://osteoperionews.bonebenders.com/en/articles/management-of-advanced-peri-implantitis-with-staged-explantation-and-delayed-re-42041665 https://osteoperionews.bonebenders.com/en/articles/management-of-advanced-peri-implantitis-with-staged-explantation-and-delayed-re-42041665 Tue, 07 Apr 2026 00:00:00 GMT Advanced peri-implantitis in the esthetic zone represents one of the most demanding clinical scenarios in implant dentistry: bone loss is often extensive, soft tissue architecture is compromised, and the stakes — both functional and esthetic — are high. This article by Spînu and colleagues addresses a question that many clinicians face but few protocols clearly answer: when explantation is inevitable, how should it be staged, and when is the right moment to re-implant? The authors present a cas Dentistry journal https://osteoperionews.bonebenders.com/en/articles/comparative-effect-of-non-surgical-versus-surgical-therapy-for-stage-iiiiv-perio-42035718 https://osteoperionews.bonebenders.com/en/articles/comparative-effect-of-non-surgical-versus-surgical-therapy-for-stage-iiiiv-perio-42035718 Sat, 25 Apr 2026 00:00:00 GMT Advanced periodontitis — Stage III and IV — remains one of the most demanding conditions in clinical periodontics, where the choice between non-surgical periodontal therapy (NSPT) and surgical periodontal therapy (SPT) is frequently debated but rarely supported by large-scale comparative data, particularly in Asian populations. This retrospective cohort study from China addresses that gap directly. The study enrolled 3,194 patients diagnosed with Stage III/IV periodontitis who underwent periodo International dental journal https://osteoperionews.bonebenders.com/en/articles/prevalence-of-peri-implant-diseases-in-patients-with-type-2-diabetes-mellitus-a-42035463 https://osteoperionews.bonebenders.com/en/articles/prevalence-of-peri-implant-diseases-in-patients-with-type-2-diabetes-mellitus-a-42035463 Wed, 01 Apr 2026 00:00:00 GMT The relationship between type 2 diabetes mellitus (T2DM) and periodontal disease is well established — T2DM acts as a grade modifier in periodontitis, amplifying the inflammatory response and impairing tissue healing. Whether this systemic burden translates equally to peri-implant tissues, however, remains a matter of active investigation. This cross-sectional study by Sbricoli et al. set out to quantify the prevalence of peri-implant diseases in diabetic versus non-diabetic patients, providing Clinical and experimental dental research https://osteoperionews.bonebenders.com/en/articles/extent-of-implantoplasty-in-the-combined-surgical-therapy-of-peri-implantitis-a-42026938 https://osteoperionews.bonebenders.com/en/articles/extent-of-implantoplasty-in-the-combined-surgical-therapy-of-peri-implantitis-a-42026938 Wed, 01 Apr 2026 00:00:00 GMT Peri-implantitis management remains one of the most clinically demanding challenges in implant dentistry. A central unresolved question concerns the role of implantoplasty — mechanical surface decontamination through carbide bur recontouring — and specifically how far it should extend into the defect architecture to maximize outcomes. This single-center, prospective, quasi-randomized controlled trial by Monje and colleagues addressed precisely that question, comparing two approaches within a co Clinical implant dentistry and related research https://osteoperionews.bonebenders.com/en/articles/clinical-efficacy-of-hyaluronic-acid-in-peri-implantitis-treatment-a-systematic-42006458 https://osteoperionews.bonebenders.com/en/articles/clinical-efficacy-of-hyaluronic-acid-in-peri-implantitis-treatment-a-systematic-42006458 Thu, 01 Jan 2026 00:00:00 GMT Peri-implantitis remains one of the most challenging complications in implant dentistry, and the search for effective adjunctive therapies continues to drive clinical research. This systematic review by Khayat examines whether hyaluronic acid (HA), when used as an adjunct to conventional treatment, improves clinical, radiographic, and biological outcomes in patients with peri-implantitis. Following PRISMA 2020 guidelines, the author searched five databases through February 2025, identifying six Biomaterial investigations in dentistry https://osteoperionews.bonebenders.com/en/articles/a-novel-dual-anchoring-technique-for-keratinized-tissue-augmentation-in-posterio-42030755 https://osteoperionews.bonebenders.com/en/articles/a-novel-dual-anchoring-technique-for-keratinized-tissue-augmentation-in-posterio-42030755 Thu, 23 Apr 2026 00:00:00 GMT Achieving adequate keratinized tissue width (KTW) around implants in the posterior mandible remains one of the more demanding soft tissue challenges in implantology. The free gingival graft (FGG) is the gold standard for KTW augmentation, yet graft contraction — particularly in a region subject to muscular pull and limited access — can significantly undermine the final result. This retrospective case series by Yang et al. introduces a Dual Anchoring Technique (DAT) designed to mechanically stabi International dental journal