Osteoperionews

At 25 years, peri-implantitis doubles — the lesson from the Bern cohort

Sat, 01 Aug 2026 00:00:00 GMT

In brief: Implant survival 94.0% and success 90.8% at 25 years — but peri-implantitis rises from 3.5% to 9.1% (implant level) and 10% to 18.1% (patient…

L-PRF in intrabony defects: a real 1.1 mm gain, but evidence stays weak

Thu, 09 Jul 2026 00:00:00 GMT

In brief: 23 RCTs pooled: L-PRF+OFD vs OFD alone at 9 months 1.11 mm PPD reduction and 1.13 mm CAL gain, statistically significant

Short implants vs vertical GBR: the 8-year model favors the simpler choice

Fri, 10 Jul 2026 00:00:00 GMT

In brief: 8-year microsimulation model: short implants (6-8.5mm) without GBR vs regular (>10mm) with vertical GBR

Immediate implants in diabetics survive — but bone pays the price of glycemic control

Sat, 01 Aug 2026 00:00:00 GMT

In brief: Meta-analysis of 10 studies (1,350 patients, 1,623 implants): implant survival does NOT differ between diabetics and healthy patients,…

A statin as antibiotic adjuvant: flushing out P. gingivalis hiding inside host cells

Thu, 09 Jul 2026 00:00:00 GMT

In brief: P. gingivalis invades host cells and evades extracellular antibiotics, fueling recurrence

At 20 years implants hold up like natural teeth — but only with maintenance

Fri, 19 Jun 2026 00:00:00 GMT

In brief: Over 20 years, implants and contra-lateral teeth showed comparable attachment loss (~4.5 vs ~4.4 mm) and survival in maintained periodontitis…

Antibiotics add half a millimetre in peri-implantitis — local beats systemic

Thu, 01 Jan 2026 00:00:00 GMT

In brief: Across 22 RCTs, adjunctive antibiotics improved PPD by ~0.69 mm and CAL by ~0.55 mm over debridement alone — statistically significant,…

Xenogeneic blocks match autogenous bone at 4 years — except in the esthetic zone

Thu, 01 Jan 2026 00:00:00 GMT

In brief: At 4 years, collagenated xenogeneic and autogenous bone blocks gave comparable implant survival and success after lateral ridge augmentation.

Fascia lata allograft thickens peri-implant mucosa without a palatal harvest

Tue, 23 Jun 2026 00:00:00 GMT

In brief: In a 16-patient pilot RCT, fascia lata allograft and connective tissue graft both significantly increased peri-implant mucosal thickness and…

Patients on Ozempic-class drugs: a risk modifier in perio, not a treatment

Thu, 11 Jun 2026 00:00:00 GMT

In brief: GLP-1 receptor agonists may affect periodontal tissues both indirectly (glycemic control, weight, inflammation) and directly (GLP-1R / DPP-4…

Past 10 cigarettes a day, GBR implants lose twice the bone

Tue, 16 Jun 2026 00:00:00 GMT

In brief: In this 5-year cohort, smokers of >10 cigarettes/day lost about twice the marginal bone (2.67 mm) of non- and light smokers (1.34-1.40 mm).

PEEK or titanium mesh for the ridge? They tie once you control the graft

Tue, 16 Jun 2026 00:00:00 GMT

In brief: RCT in 14 patients (28 sites): no significant difference in horizontal bone gain between prebent titanium mesh (3.02 mm) and customized PEEK…

Thin-phenotype lower recessions: the tunnel beats the envelope flap

Tue, 16 Jun 2026 00:00:00 GMT

In brief: RCT in 59 patients (103 lower-incisor sites, thin phenotype): at 6 months the tunnel + CTG gave 79% mean root coverage vs 58% for the envelope…

Putting a number on periodontitis as cardiovascular risk: a proposed score

Wed, 01 Jul 2026 00:00:00 GMT

In brief: A narrative review proposing the Endothelial Risk Score (ERS): it combines Periodontal Inflamed Surface Area (PISA) with age, sex, systolic BP,…

Oral disease leads NCD prevalence — and periodontal disability rises with wealth

Sat, 01 Aug 2026 00:00:00 GMT

In brief: In 2023, oral disorders in Latin America and the Caribbean caused 308 million prevalent cases and 2.41 million years lived with disability —…

GBR membranes: a 26% complication rate forces a rethink beyond passive occlusion

Thu, 01 Oct 2026 00:00:00 GMT

In brief: A meta-analysis of 100 studies puts GBR complication rates near 26%, exposing the structural limits of conventional collagen and PTFE membranes.

Augmented vs native posterior mandible: which bone hosts healthier implants at 15 years?

Mon, 01 Jun 2026 00:00:00 GMT

In brief: Implant survival was nearly identical at 15 years: 94.7% in native bone, 95.3% in augmented bone.

Peri-implantitis debridement: less than 1 mm cleaned in this SEM cohort

Thu, 30 Apr 2026 00:00:00 GMT

In brief: SEM analysis of 49 explanted implants found a mean contaminant-free zone of just 0.66 mm (range 0–3.0 mm).

Perio therapy as CVD prevention: cost-effective only over a lifetime horizon

Wed, 10 Jun 2026 00:00:00 GMT

In brief: Over a 25-year horizon, NSPT reached an ICER of €19,322/QALY — within NICE thresholds; at 10 years the ICER more than doubled to €49,847.

EMD at 30: where the evidence holds — and where it does not

Thu, 01 Jan 2026 00:00:00 GMT

In brief: EMD remains a validated adjunct for recession coverage and intrabony defects, with consistent evidence across 30 years of literature.

Full-arch implants: what 29 Italian experts agreed on — and what it changes in practice

Mon, 11 May 2026 00:00:00 GMT

In brief: Four implants in the mandibular full-arch show comparable survival to six, per the consensus statements.

Regeneration then orthodontics: 20-year tooth survival in Stage IV periodontitis

Thu, 28 May 2026 00:00:00 GMT

In brief: In this cohort, 89.1% estimated tooth survival at 20 years for severely compromised teeth (PPD ≥7 mm, intrabony defect, pathologic migration)…

Short implants at 10 years: viable for the atrophic ridge, but survival stays below standard implants

Mon, 01 Jun 2026 00:00:00 GMT

In brief: Pooled 10-year survival was 91–94% (patient/implant level); sensitivity analysis returned the more conservative 89.7–92.8%.

Simultaneous GBR with a 3D preformed PLGA membrane: 87% bone gain maintained at 5 months, zero exposures

Thu, 04 Jun 2026 00:00:00 GMT

In brief: In this 21-site single-arm study, mean horizontal bone augmentation was 2.99 mm with 87.2% of hard tissue gain preserved at 5 months.

Connective Tissue Graft Under Pontics: Early Gain, Uncertain Long-Term Edge

Sat, 16 May 2026 00:00:00 GMT

In brief: CTG reliably improves ridge contour and soft-tissue volume at pontic sites in the short term.

Full-arch implant prostheses: the implants survive, but material choice drives complication risk

Wed, 13 May 2026 00:00:00 GMT

In brief: Prosthesis survival was 92.3% and implant loss 4.2% over a mean 6.8 years — high reliability in this cohort.

Periodontal disease starts in childhood — but Asia's data can't yet prove how often

Sat, 23 May 2026 00:00:00 GMT

In brief: Gingivitis was the dominant finding across 84 studies from 24 Asian countries, with prevalence spanning under 10% to 100% — a range that…

Socket Shield: FEA points to 120-150° arc as the biomechanical sweet spot for the retained fragment

Thu, 21 May 2026 00:00:00 GMT

In brief: In this finite element model, a labial arc angle of 120-150° for the retained root fragment produced the most balanced stress distribution…

Zirconia vs titanium for overdentures: a 14-point success gap and more bone loss at 3 years

Sun, 24 May 2026 00:00:00 GMT

In brief: In this 3-year split-mouth RCT, titanium implant success (91.7%) outpaced zirconia (77.8%) by nearly 14 percentage points.

Autonomous robotics for transcrestal sinus elevation: submillimetre trueness in a first cohort

Fri, 22 May 2026 00:00:00 GMT

In brief: In this 12-implant cohort, autonomous robotic placement achieved mean global deviations of 0.58 mm (coronal) and 0.64 mm (apical), with 1.19°…

SRP alone beats the adjunct: NaOCl/AA gel adds no microbiological benefit in this RCT

Mon, 25 May 2026 00:00:00 GMT

In brief: A single 30-second NaOCl/AA gel application during SRP produced no additional microbiological benefit over mechanical debridement alone.

PRF and platelet concentrates in bone regeneration: adjunct, not replacement — what the evidence actually supports

Fri, 08 May 2026 00:00:00 GMT

In brief: L-PRF and A-PRF show clinically relevant adjunctive benefit in periodontal intrabony defects, correlating with improved CAL gain and faster soft…

Free gingival graft donor site: CTA alone shortens closure time and reduces mid-healing pain

Fri, 22 May 2026 00:00:00 GMT

In brief: In this 60-patient RCT, α-cyanoacrylate adhesive alone shortened intraoperative wound closure time significantly vs both suture-based groups…

Plasma-activated healing abutments: a histological signal at the epithelial interface

Sat, 23 May 2026 00:00:00 GMT

In brief: Plasma activation of healing abutments produced lower inflammation scores in the basal zone only (P = 0.04); upper and intermediate zones showed…

Implants at 20 years: a 93% survival rate — but half of failures are mechanical, not biological

Fri, 22 May 2026 00:00:00 GMT

In brief: Pooled 20-year survival was 93.0% (CI 91.6–94.1%) across 1,028 implants in prospective studies — a reassuring baseline figure for patient…

Implants in diabetes: HbA1c below 7% is the threshold, not the diagnosis

Sat, 23 May 2026 00:00:00 GMT

In brief: Well-controlled diabetics (HbA1c ≤7%) showed outcomes comparable to non-diabetic patients in this review.

Mandibular bone repair: the periosteal stem-cell switch that could replace grafts

Thu, 21 May 2026 00:00:00 GMT

In brief: The PLAGL1-KLF4-IRX5 transcription factor axis controls osteoblast differentiation of periosteal stem/progenitor cells in the mandible.

Gut dysbiosis as a causal driver of periodontal bone loss: FMT evidence in a mouse model

Sat, 23 May 2026 00:00:00 GMT

In brief: In a combined UC + periodontitis mouse model, gut dysbiosis causally doubled alveolar bone loss via fecal microbiota transplantation.

Dentine vs e-PRF for GBR: equivalent outcomes, your choice

Thu, 21 May 2026 00:00:00 GMT

In brief: In this 40-patient RCT, DDBM and e-PRF produced identical implant survival (100%) and marginal bone loss (~1.2–1.3 mm buccal) at 24 months.

Tissue-level implants at 25 years: prosthesis design doesn't drive bone loss — suppuration does

Mon, 01 Jun 2026 00:00:00 GMT

In brief: After 25 years, crestal bone loss and peri-implantitis prevalence did not differ significantly between single crowns, splinted crowns, or…

ISQ at placement: useful stability indicator, but not a predictor of long-term survival

Mon, 01 Jun 2026 00:00:00 GMT

In brief: ISQ shows a moderate, statistically significant correlation with insertion torque (pooled r = 0.44) across 20 pooled studies, but shared…

Attached gingiva width: not an independent bone-loss driver in this 5-year cohort

Wed, 13 May 2026 00:00:00 GMT

In brief: In univariate analysis, implants with <2 mm attached gingiva showed greater mean bone loss (2.17 vs 1.64 mm), but this difference did not…

FGG vs. collagen matrix for peri-implant keratinized tissue: autograft wins at 6 months

Thu, 01 Jan 2026 00:00:00 GMT

In brief: In this RCT, FGG produced significantly greater keratinized tissue width and soft tissue thickness than XCM at all three follow-up points (1, 3,…

Peri-implantitis destroys faster with less bacteria: the vascular signature that explains it

Fri, 08 May 2026 00:00:00 GMT

In brief: In this large single-cell dataset (967,000+ cells), peri-implantitis tissues showed lower bacterial load and microbial diversity than…

Naringin curbs alveolar bone loss in rat periodontitis — via NLRP3 and the gut axis

Thu, 14 May 2026 00:00:00 GMT

In brief: In a rat ligature model, naringin reduced alveolar bone loss and suppressed NLRP3 inflammasome activation via the AMPK/Nrf2 pathway.

Allogeneic bone plug vs DBBM for GBR: comparable bone, faster turnover in pilot RCT

Wed, 13 May 2026 00:00:00 GMT

In brief: At 6 months, vital bone fraction did not differ significantly between ACBP and DBBM (38.8% vs 32.2%, P=0.105) in this pilot RCT.

One-piece vs. two-piece implants at 15+ years: better bone, but at what cost?

Mon, 01 Jun 2026 00:00:00 GMT

In brief: Overall implant survival reached 95% at 15-17 years, with two-piece implants showing higher survival (98.0%) than one-piece (91.8%) in this…

Silver-coated implants curb bone loss in peri-implantitis — but only in mice, so far

Thu, 14 May 2026 00:00:00 GMT

In brief: Ag⁺ ions on a hydroxyapatite/IP6 coating showed significant antibacterial activity against P. gingivalis in vitro.

Periodontitis and muscle loss: gingival activin A as a systemic mediator

Wed, 06 May 2026 00:00:00 GMT

In brief: In a mouse model, periodontitis reduced skeletal muscle mass through elevated circulating activin A, independent of food intake or fat mass…

Healthy implants, higher MMP-8: subclinical tissue stress before any clinical sign

Thu, 01 Jan 2026 00:00:00 GMT

In brief: In this matched-pair cohort, clinically healthy implants showed MMP-8 levels approximately 29% higher than adjacent homologous teeth (p<0.05).